News > Chemical found in Splenda damages DNA: ‘Genotoxic’ discovery

Chemical found in Splenda damages DNA: ‘Genotoxic’ discovery

New research published in the Journal of Toxicology and Environmental Health suggests that the artificial sweetener Splenda, or sucralose, may have detrimental health effects. Sucralose-6-acetate, a compound formed when sucralose breaks down in the body, was found to damage the intestinal lining and increase the expression of genes associated with inflammation, oxidative stress, and cancer. The study used human tissue, making the findings directly relevant to the human body.